1597005

Quinine sulfate

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): Quinine hemisulfate salt monohydrate
• 실험식(Hill 표기법): C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O
• CAS Number: 207671-44-1
• Molecular Weight: 391.47
• Beilstein: 6113937
• MDL number: MFCD00150790
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329751013
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: quinine
• 분자량: monograph mol wt. 782.94
• 제조업체/상표: USP
• mp: ~225 °C (dec.) (lit.)
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
• InChI: 1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
• InChI key: ZHNFLHYOFXQIOW-LPYZJUEESA-N

설명

일반 설명

(C₂₀H₂₄N₂O₂)₂ . H₂SO₄ . 2H₂O

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Quinine sulfate is the sulfate salt of quinine, an alkaloid, obtained from the bark of Cinchona species.

애플리케이션

Quinine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Quinine Sulfate Capsules
• Quinine Sulfate Tablets

생화학적/생리학적 작용

Potassium channel blocker. Antimalarial

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable