SML0517

Amlexanox

≥98% (HPLC)

• 동의어(들): 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]Benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3673
• 실험식(Hill 표기법): C₁₆H₁₄N₂O₄
• CAS Number: 68302-57-8
• Molecular Weight: 298.29
• MDL number: MFCD00864790
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825526
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL at warmed, clear
• 배송 상태: wet ice
• 저장 온도: −20°C
• SMILES string: CC(C)c1ccc2Oc3nc(N)c(cc3C(=O)c2c1)C(O)=O
• InChI: 1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
• InChI key: SGRYPYWGNKJSDL-UHFFFAOYSA-N
• 유전자 정보: human ... PDE4A(5141) , PDE4B(5142) , PDE4C(5143) , PDE4D(5144)

설명

일반 설명

Amlexanox is an anti-allergic drug with anti-inflammatory properties.

생화학적/생리학적 작용

Amlexanox elevates the amount of nonsense-containing mRNAs in treated cells and helps to generate full-length proteins effectively.

Amlexanox is an anti-allergy and anti-asthma drug that blocks histamine and leukotriene release from leukocytes and mast cells. Amlexanox has also been shown to inhibit cahaperone activity of Hsp90, and S100A13, which is involved in transport of proteins devoid of signal peptide sequences.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable