S8251

Succinylcholine chloride dihydrate

98.0-102.0%, solid

• 동의어(들): Bis(trimethylammonioethyl) succinate chloride, Succinyldicholine dichloride
• Linear Formula: [(CH₃)₃NCH₂CH₂OCOCH₂]₂Cl₂ · 2H₂O
• CAS Number: 6101-15-1
• Molecular Weight: 397.34
• Beilstein: 3922827
• EC Number: 200-747-4
• MDL number: MFCD00150564
• UNSPSC 코드: 41116107
• PubChem Substance ID: 24277873
• NACRES: NA.77

속성

• 분석: 98.0-102.0%
• 형태: solid
• 색상: white
• solubility: H₂O: complete 100 mg/ml, clear to slightly hazy, colorless; H₂O: soluble (unstable at pH > 9.)
• 주관자: Novartis
• SMILES string: O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
• InChI: 1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2
• InChI key: FFSBEIRFVXGRPR-UHFFFAOYSA-L

설명

애플리케이션

Succinylcholine chloride dehydrate was used to study the mechanism of gating of Cys loop receptors in Xenopus laevis.^4,5

생화학적/생리학적 작용

Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.

Succinylcholine is a cholinergic antagonist and a neuromuscular blocking agent. It induces depolarization of acetylcholine receptors on the muscle membrane and efflux of potassium from the muscle that leads to hypokalemia in individuals with upregulated expression of acetylcholine receptors.³

특징 및 장점

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

재구성

Solutions may be stored for several days at 4 °C.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)