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Merck
모든 사진(4)

Key Documents

S1885

Sigma-Aldrich

Suberic acid bis(N-hydroxysuccinimide ester)

≥95%, powder

동의어(들):

Disuccinimidyl suberate, Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS)

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About This Item

실험식(Hill 표기법):
C16H20N2O8
CAS Number:
Molecular Weight:
368.34
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.21

Quality Level

분석

≥95%

형태

powder

반응 적합성

reagent type: cross-linking reagent

solubility

chloroform: 50 mg/mL
DMF: soluble
aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)

작용기

imide

저장 온도

2-8°C

SMILES string

O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI

1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2

InChI key

ZWIBGKZDAWNIFC-UHFFFAOYSA-N

일반 설명

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

애플리케이션

Suberic acid bis(N-hydroxysuccinimide ester) has been:
  • supplemented in pierce lysis buffer used for immunoprecipitation
  • used to conjugate the oligonucleotide standards to gelatin
  • used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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