QBD10593

DBCO-dPEG ^®₁₂-MAL

• 동의어(들): Polyethylene glycol
• 실험식(Hill 표기법): C₅₂H₇₄N₄O₁₇
• Molecular Weight: 1027.16
• UNSPSC 코드: 51171641

속성

• 분석: >90%
• 형태: solid or viscous liquid
• 반응 적합성: reagent type: cross-linking reagent; reaction type: click chemistry
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O

설명

일반 설명

DBCO-dPEG^®₁₂-MAL is a versatile heterobifunctional cross-linking reagent used in strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. This approach is also known as copper-free click chemistry. The presence of maleimidopropyl (MAL) functional group in the reagent forms a thiol-ether linkage with sulfhydryl groups.

특징 및 장점

DBCO-dPEG ^®₁₂-MAL can be used to conjugate two different proteins or an antibody with a payload by using copper-free "click" chemistry with the DBCO and reaction of the maleimide with a free thiol.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable