P246

Monoclonal Anti-PSD95 antibody produced in mouse

clone 7E3-1B8, purified immunoglobulin, buffered aqueous solution

• 동의어(들): Anti-MRD62, Anti-PSD95, Anti-SAP-90, Anti-SAP90
• MDL number: MFCD01324382
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 7E3-1B8, monoclonal
• 형태: buffered aqueous solution
• 분자량: antigen 95 kDa
• 종 반응성: rat
• 기술: immunofluorescence: 1:500; immunoprecipitation (IP): suitable; western blot: 1:2,000
• 동형: IgG2a
• UniProt 수납 번호: P31016
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: rat ... Dlg4(29495)

설명

일반 설명

DLG4 (discs large MAGUK scaffold protein 4) gene codes for the postsynaptic density-95 (PSD95) protein. Postsynaptic density 95 (PSD-95), a synaptic scaffolding protein is also a membrane-associated guanylate kinase (MAGUK) family protein. It has three PDZ domains on the N terminus followed by a Src homology 3 (SH3) domain and a guanylate kinase (GK) domain. This gene is located on human chromosome 17p13.1.

특이성

Reacts with both the recombinant and native rat PSD95. By immunofluorescence with rat hippocampal cells, a staining pattern coincident with NMDA receptor staining at synaptic sites consistent with its proposed role in receptor clustering is observed. Fixation with cold methanol is recommended.

면역원

recombinant rat PSD95 (post synaptic density 95 kDa).

애플리케이션

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Immunofluorescence (1 paper)
Western Blotting (1 paper)

생화학적/생리학적 작용

Postsynaptic density 95 (PSD-95) plays a major role in bidirectional synaptic plasticity, an important process, essential for learning and memory. It exhibits increased dynamics upon induction of plasticity.

물리적 형태

Solution in phosphate buffered saline containing 0.05% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)