O1008

Oleic acid

≥99% (GC)

• 동의어(들): 9Z-Octadecenoic acid, cis-Oleic acid, cis-9-Octadecenoic acid, Elainic acid
• Linear Formula: CH₃(CH₂)₇CH=CH(CH₂)₇COOH
• CAS Number: 112-80-1
• Molecular Weight: 282.46
• Beilstein: 1726542
• EC Number: 204-007-1
• MDL number: MFCD00064242
• UNSPSC 코드: 12352211
• PubChem Substance ID: 24278605
• NACRES: NA.25

속성

• 생물학적 소스: plant (Sunflower)
• Quality Level: 200
• vapor pressure: 1 mmHg ( 176 °C)
• 분석: ≥99% (GC)
• 형태: viscous liquid
• 색상: colorless to very faintly yellow
• refractive index: n20/D 1.459 (lit.)
• bp: 194-195 °C/1.2 mmHg (lit.)
• mp: 13-14 °C (lit.)
• solubility: H₂O: insoluble (practically); alcohol: soluble; benzene: soluble; chloroform: soluble; oil: soluble (fixed and volatile)
• density: 0.89 g/mL at 25 °C (lit.)
• 응용 분야: life science and biopharma; lipidomics
• 작용기: oleic acid
• 지질 유형: unsaturated FAs
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: CCCCCCCC\C=C/CCCCCCCC(O)=O
• InChI: 1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
• InChI key: ZQPPMHVWECSIRJ-KTKRTIGZSA-N
• 유전자 정보: human ... PRKCA(5578) , PRKCB(5579) , PRKCD(5580) , PRKCE(5581) , PRKCG(5582) , PRKCH(5583) , PRKCI(5584) , SOAT1(6646) , SOAT2(8435)

설명

일반 설명

Oleic acid (OA), a non-essential fatty acid, is classified as monounsaturated fatty acid (MUFA) richly present in olive oil. Its quantitative removal from the mixtures of triglyceride and partial glycerides has been reported. OA is widely used as a surfactant for the stabilization of magnetic nanoparticles. Monodisperse magnetite nanoparticles (7 and 19nm) coated with OA have been prepared.

애플리케이션

Oleic acid has been used:

• to study the effects of fatty acids on gastric cancer (GC)
• to induce lipid droplet formation in cell culture
• as an additive in the magnetorheological fluid preparation.

Oleic acid may be used in the preparation of 10-hydroxy octadecanoic acid and methyl ester of the 10-hydroxy octadecanoic acid.

생화학적/생리학적 작용

Oleic acid is known to improve immune function and health. Dietary supplement of this fatty acid contributes to the reduction in cholesterol levels, atherogenesis risk, blood pressure, and host versus graft response. Oleic acid has been proven to benefit autoimmune diseases by exhibiting anti-inflammatory action. It also ameliorates the condition of breast cancer. Oleic acid produces physiological effects such as protein kinase C activation in hepatocytes, uncoupling oxidative phosphorylation, and 2,4-dinitrophenol−stimulated ATPase inhibition. This action can be reversed by adding serum albumin.

기타 정보

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안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter