S193

Anti-Synapsin I antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• 동의어(들): Anti-EPILX, Anti-MRX50, Anti-SYN1a, Anti-SYN1b, Anti-SYNI
• MDL number: MFCD00282157
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: lyophilized powder
• 분자량: antigen ~80 kDa (Synapsin Ia)
• 종 반응성: rat, mouse, human, bovine
• 기술: dot blot: 1:1000; immunohistochemistry (frozen sections): 1:2000; immunoprecipitation (IP): 1 μg; indirect immunofluorescence: 1:2000; western blot: 1:1000
• UniProt 수납 번호: P17600
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SYN1(6853) ; mouse ... Syn1(20964) ; rat ... Syn1(24949)

설명

일반 설명

Synapsin I (1a and 1b) refers to two nearly identical phosphoproteins found in the cytoplasmic surface of synaptic vesicles of the CNS (central nervous system) and PNS(peripheral nervous system). It may be used to localize and detect synapsin I (synapsins Ia and Ib are collectively referred to as synapsin I) in nerve terminals.The SYN1 gene is mapped to human chromosome Xp11.3-p11.23.

면역원

synapsin I from bovine brain.

애플리케이션

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.

• Western Blotting (1 paper)
• immunohistochemistry
• immunoblotting
• immunoprecipitation
• ELISA.

Rabbit polyclonal anti-Synapsin I antibody can be used for the localization and detection of synapsin I (synapsins Ia and Ib, approximately 80 kDa and 77 kDa, are collectively referred to as synapsin I) in nerve terminals.

생화학적/생리학적 작용

Synapsin I is involved in the regulation of axonogenesis and synaptogenesis wherein it serves as a substrate of various protein kinases including those activated by cAMP, calciuim/calmodulin, mitogens, and cyclins. The antibody strongly reacts with the synapsin I doublet. Synapsin I is associated with vesicle trafficking. Mutation in this gene is one of the known cause for familial epilepsy and autism spectrum disorders.

물리적 형태

Lyophilized from ammonium bicarbonate (5 mM)

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)