D2534

cis-4,7,10,13,16,19-Docosahexaenoic acid

≥98%

• 동의어(들): DHA
• 실험식(Hill 표기법): C₂₂H₃₂O₂
• CAS Number: 6217-54-5
• Molecular Weight: 328.49
• Beilstein: 1715505
• MDL number: MFCD00065722
• UNSPSC 코드: 12352211
• PubChem Substance ID: 24893696
• NACRES: NA.25

속성

• 생물학적 소스: algae
• 분석: ≥98%
• 양식: liquid
• 작용기: carboxylic acid
• 지질 유형: omega FAs
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
• InChI: 1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-
• InChI key: MBMBGCFOFBJSGT-KUBAVDMBSA-N

설명

일반 설명

Docosahexaenoic acid (DHA) is abundantly present in the brain.

Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid with 22 carbons and six double bonds, the first double bond occurring at position three from the methyl terminus (22:6 n-3). It is a component of lipid membranes and myelin sheath.

애플리케이션

cis-4,7,10,13,16,19-Docosahexaenoic acid has been used:

• as a component in Dulbecco′s modified Eagle medium (DMEM) for culturing cells to perform docosahexaenoic acid (DHA) treatment
• to study its impact on human induced pluripotent stem cell (iPSC)-derived neuronal at a molecular and cellular level
• in MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay to study its cytotoxic effects on three human hepatocellular carcinoma (HCC) cell lines (HepG2, Hep3B, Huh7)

생화학적/생리학적 작용

Docosahexaenoic acid (DHA) participates in the growth and physiology of the central nervous system. It regulates adult neurogenesis and neuroplasticity. DHA plays a key role in fetal brain development. It may exhibit antioxidant and anti-inflammatory properties. DHA plays a role in the regulation of cell membrane fluidity. It plays a vital role in several brain development processes, including neurotransmitter release, gene expression, myelination, neuroinflammation, and neuronal differentiation. DHA possesses an anticancer effect in several types of cancer.

Docosahexaenoic acid (DHA) serves as a precursor for signaling molecules such as prostaglandins and eicosanoids.

포장

Sealed ampule.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 143.6 °F - closed cup
• Flash Point (°C): 62 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)