N0756

N-Nitrosodiethylamine

liquid, nitrosamine

• 동의어(들): Diethylnitrosamine
• Linear Formula: (C₂H₅)₂NNO
• CAS Number: 55-18-5
• Molecular Weight: 102.14
• Beilstein: 1744991
• EC Number: 200-226-1
• MDL number: MFCD00013890
• UNSPSC 코드: 12352116
• PubChem Substance ID: 24897440
• NACRES: NA.77

속성

• product name: N-Nitrosodiethylamine, liquid
• 형태: liquid
• Quality Level: 100
• 색상: yellow
• bp: 177 °C (lit.)
• density: 0.95 g/mL (lit.)
• SMILES string: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• InChI key: WBNQDOYYEUMPFS-UHFFFAOYSA-N

설명

일반 설명

N-Nitrosodiethylamine belongs to the nitrosamines category of nitrogenous disinfection byproduct. It is also generated in chlorine based water treatment plants.

애플리케이션

N-Nitrosodiethylamine has been used to induce hepatocarcinogenesis in rat and mice.

생화학적/생리학적 작용

N-Nitrosodiethylamine (NDMA) is carcinogenic in all animal species tested. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. NDMA is acted upon by the cytochrome P450 system resulting in the formation of carcinogenic methyldiazonium ion. However microbes like Pseudomonas metabolize NDMA into N-nitromethylamine (NTMA) and formaldehyde.

포장

Bulk Package

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H301,H350,H412
• 예방조치 성명서: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter