추천 제품
Quality Level
분석
≥99.0% (GC)
양식
liquid
IVD
for in vitro diagnostic use
bp
177 °C (lit.)
density
0.95 g/mL (lit.)
작용기
N-nitroso
amine
nitroso
SMILES string
CCN(CC)N=O
InChI
1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
InChI key
WBNQDOYYEUMPFS-UHFFFAOYSA-N
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관련 카테고리
애플리케이션
N-Nitrosodiethylamine can be used as a reactant to synthesize:
- α-Amino oxime derivatives from alkenes via visible-light-induced photoaddition in the presence of HCl.
- Diethylnitrosamine metalloporphyrin complexes from metalloporphyrins in the presence of dichloromethane.
N-Nitrosodiethylamine can also be used in the synthesis of 1,1-diethylhydrazine.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
개인 보호 장비
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
이미 열람한 고객
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N-Nitrosodiethylamine (NDEA) is DNA reactive after bioactivation and produces tumors in every animal species tested. Bioactivation is effected by several P450 isozymes including CYP2E1, which is ethanol inducible. Tumor formation in rat liver was proportional to O4-ethyldeoxythymidine formation in DNA
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STAT3 activation is involved in development and progression of hepatocellular carcinoma (HCC). We investigated STAT3 activation during hepatocarcinogenesis induced by neonatal diethylnitrosamine (DEN) treatment in mice. Nuclear accumulation and phosphorylation of STAT3 were detected in altered hepatocyte foci in the
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