N0258

N-Nitrosodiethylamine

ISOPAC^®

• 동의어(들): Diethylnitrosamine
• Linear Formula: (C₂H₅)₂NNO
• CAS Number: 55-18-5
• Molecular Weight: 102.14
• Beilstein: 1744991
• EC Number: 200-226-1
• MDL number: MFCD00013890
• UNSPSC 코드: 12352116
• PubChem Substance ID: 24897417
• NACRES: NA.25

속성

• 양식: liquid
• bp: 177 °C (lit.)
• density: 0.95 g/mL (lit.)
• SMILES string: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• InChI key: WBNQDOYYEUMPFS-UHFFFAOYSA-N

설명

애플리케이션

N-Nitrosodiethylamine (NDEA) has been used as a hepatocarcinogen/DNA damaging agent. It has been used as a calibration standard for gas–liquid chromatography.

생화학적/생리학적 작용

N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

포장

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

주의사항

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

재구성

Dissolving the contents in 100 mL of solvent yields a 1% solution.

법적 정보

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H301,H350,H412
• 예방조치 성명서: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter