추천 제품
생물학적 소스
rat
Quality Level
재조합
expressed in E. coli
분석
≥97% (SDS-PAGE)
양식
lyophilized powder
분자량
15.5 kDa
포장
pkg of 0.1 mg
기술
cell culture | mammalian: suitable
불순물
endotoxin, tested
색상
white
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
rat ... Ifng(25712)
애플리케이션
Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.
생화학적/생리학적 작용
Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.
특징 및 장점
The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Sally Abdelmoaty et al.
PloS one, 8(9), e75543-e75543 (2013-10-03)
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if
Meager, A. et al.
Lymphokines and Interferons, A Practical Approach, 129-129 (1987)
R Dijkema et al.
The EMBO journal, 4(3), 761-767 (1985-03-01)
The chromosomal immune interferon gene of the rat (IFN-gamma) was identified by screening a recombinant rat lambda phage library with a human IFN-gamma cDNA probe. In contrast to the genes of other rat IFNs, this rat IFN-gamma chromosomal gene contains
Hamid Reza Jafarinaveh et al.
Iranian journal of allergy, asthma, and immunology, 13(2), 125-130 (2013-12-18)
Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because
Yoshifumi Saisho et al.
American journal of physiology. Endocrinology and metabolism, 296(1), E89-E96 (2008-10-23)
An obstacle to development of methods to quantify beta-cell turnover from pancreas tissue is the lack of conversion factors for the frequency of beta-cell replication or apoptosis detected by immunohistochemistry to rates of replication or apoptosis. We addressed this obstacle
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