추천 제품
생물학적 소스
mouse
Quality Level
재조합
expressed in E. coli
분석
≥98% (SDS-PAGE)
양식
lyophilized powder
분자량
protein 15.6 kDa
포장
pkg of 0.1 mg
기술
cell culture | mammalian: suitable
불순물
endotoxin, tested
색상
white
solubility
water: soluble 1.000 mL, clear, colorless
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
mouse ... Ifng(15978)
애플리케이션
Interferon-γ from mouse has been used:
- for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c+ (CD11 antigen-like family member C) lung macrophages
- for stimulation of murine macrophages to induce the production of nitrite and nitrate
- to check CCAAT/enhancer binding protein β (C/EBPβ)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation
생화학적/생리학적 작용
Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.
물리적 형태
Lyophilized from a 0.2 μm filtered buffered solution. Package size based on protein content.
분석 메모
The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Sergio Arias-Negrete et al.
Analytical biochemistry, 328(1), 14-21 (2004-04-15)
Preparation of a nitrate reductase lysate of Escherichia coli MC1061 to measure nitrate and nitrite in biologic fluids is described. To obtain the crude bacterial lysate containing nitrate reductase activity, E. coli MC1061 was subjected to 16-20 freeze-thawing cycles, from
S N Vogel et al.
Infection and immunity, 38(2), 681-685 (1982-11-01)
Silica has been used for many years as an agent which selectively alters macrophage functions and, as such, has been used to assess the role of macrophages in the immune response to a variety of microbial and chemically defined agents.
P W Gray et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(19), 5842-5846 (1983-10-01)
The murine immune interferon (IFN-gamma) gene was cloned and expressed under control of the simian virus 40 early promoter in the monkey COS-1 cell line. A protein is secreted from these cells having the biological, antigenic, and biochemical characteristics of
Marta Pulido-Salgado et al.
Scientific reports, 8(1), 16096-16096 (2018-11-02)
Microglia, the main resident immune cells in the CNS, are thought to participate in the pathogenesis of various neurological disorders. LPS and LPS + IFNγ are stimuli that are widely used to activate microglia. However, the transcriptomic profiles of microglia treated with
Andre Heinen et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 27(1), 46-58 (2018-12-12)
Insulin-like growth factor 1 (IGF1) is an anabolic hormone that controls the growth and metabolism of many cell types. However, IGF1 also mediates cardio-protective effects after acute myocardial infarction (AMI), but the underlying mechanisms and cellular targets are not fully
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