C8667

Cholesterol

Sigma Grade, ≥99%

• 동의어(들): 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
• 실험식(Hill 표기법): C₂₇H₄₆O
• CAS Number: 57-88-5
• Molecular Weight: 386.65
• Beilstein: 1915888
• EC Number: 200-353-2
• MDL number: MFCD00003646
• UNSPSC 코드: 12352111
• eCl@ss: 39023139
• PubChem Substance ID: 24893094
• NACRES: NA.77

속성

• 생물학적 소스: sheep wool
• Quality Level: 200
• Grade: Sigma Grade
• 분석: ≥99%
• 형태: powder
• bp: 360 °C (lit.)
• mp: 147-149 °C (lit.)
• solubility: water: soluble 0.00003 g/L at 20 °C
• density: 1.067 g/mL at 25 °C (lit.)
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI key: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• 유전자 정보: human ... POLA1(5422) , TOP2A(7153) ; rat ... Ar(24208) , Polb(29240)

설명

애플리케이션

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

Standard for chromatography

생화학적/생리학적 작용

Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

제조 메모

Cholesterol monohydrate yields a clear, colorless to faint yellow solution in hot alcohol. It is also soluble in acetone, dioxane, ethyl acetate, benzene, petroleum ether, oils, fats, and in aqueous solutions of bile salts. Solutions should be protected from light.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)