850725P

18:1 (Δ9-Cis) PE (DOPE)

Avanti Polar Lipids

• 동의어(들): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; DOPE; PE(18:1(9Z)/18:1(9Z)); 110635, DOPE
• 실험식(Hill 표기법): C₄₁H₇₈NO₈P
• CAS Number: 4004-05-1
• Molecular Weight: 744.03
• UNSPSC 코드: 51191904
• NACRES: NA.25

속성

• 설명: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
• 분석: >99% (TLC)
• 형태: powder
• 포장: pkg of 1 × 1 g (850725P-1g); pkg of 2 × 100 mg (850725P-200mg); pkg of 5 × 100 mg (850725P-500mg); pkg of 1 × 25 mg (850725P-25mg)
• 제조업체/상표: Avanti Polar Lipids
• 응용 분야: advanced drug delivery
• 지질 유형: cardiolipins; phospholipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
• InChI: 1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1
• InChI key: MWRBNPKJOOWZPW-NYVOMTAGSA-N

설명

일반 설명

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (18:1 (Δ9-Cis) PE (DOPE)) is a neutral phospholipid and displays sensitivity towards pH change. At acidic it is an inverted hexagonal micelle and transforms to spherical micelle at alkaline pH.

애플리케이션

18:1 (Δ9-Cis) PE (DOPE) has been used in the preparation of liposome for human uncoupling protein 1 (UCP1) reconstitution and for Caenorhabditis elegans autophagy related cysteine protease protein conjugation studies. It has also been used for the generation of giant unilamellar vesicles (GUVs) for septin induced deformation studies.

생화학적/생리학적 작용

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (18:1 (Δ9-Cis) PE (DOPE)) forms a stable lipid layer and rapidly fuses with endosomal lipid bilayer. DOPE in combination with 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) has high in vitro transfection efficiency.

포장

20 mL Clear Glass Screw Cap Vial (850725P-1g)

5 mL Clear Glass Sealed Ampule (850725P-200mg)

5 mL Clear Glass Sealed Ampule (850725P-25mg)

5 mL Clear Glass Sealed Ampule (850725P-500mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable