700001P

DC-Cholesterol HCl

Avanti Polar Lipids 700001P, powder

• 동의어(들): 3β-[N-(N′,N′-dimethylaminoethane)-carbamoyl]cholesterol hydrochloride
• 실험식(Hill 표기법): C₃₂H₅₇N₂O₂Cl
• CAS Number: 166023-21-8
• Molecular Weight: 537.26
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 형태: powder
• 포장: pkg of 1 × 1 g (700001P-1g); pkg of 1 × 200 mg (700001P-200mg); pkg of 1 × 25 mg (700001P-25mg); pkg of 1 × 500 mg (700001P-500mg)
• 제조업체/상표: Avanti Polar Lipids 700001P
• 응용 분야: vaccine development
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@](C1)(OC(NCC[N+](C)([H])C)=O)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](C)CCCC(C)C.[Cl-]
• InChI: 1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H
• InChI key: ISXSJGHXHUZXNF-UHFFFAOYSA-N

설명

일반 설명

DC-Cholesterol HCl is a cholesterol derivative and a cationic lipid with a head group and linker moiety.

DC-Cholesterol HCl is a sterol-based transfection reagent.

애플리케이션

DC-Cholesterol HCl is suitable:

• for the preparation of ultrasound cationic microbubbles
• to prepare liposomes
• for the preparation of L-glutathione (GSH), loaded proliposomes

DC-Cholesterol HCl may be used in the preparation of colloidal dispersions for transmission electron microscopy studies. It may also be used in liposome preparation for assessing hexokinase activity, poly (lactic-coglycolicacid) loading and in mRNA transfection studies.

생화학적/생리학적 작용

DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).

DC-cholesterol is a cationic lipid, known to be the most efficient in gene transfection study.

포장

20 mL Clear Glass Screw Cap Vial (700001P-1g)

20 mL Clear Glass Screw Cap Vial (700001P-500mg)

5 mL Amber Glass Screw Cap Vial (700001P-200mg)

5 mL Amber Glass Screw Cap Vial (700001P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable