C1112

CP-55940

>98% (HPLC), powder

• 동의어(들): 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
• 실험식(Hill 표기법): C₂₄H₄₀O₃
• CAS Number: 83002-04-4
• Molecular Weight: 376.57
• MDL number: MFCD00673965
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278295
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: >98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D -24 to -30°, c = 0.2 in chloroform-d
• 약물 제어: regulated under CDSA - not available from Sigma-Aldrich Canada
• 저장 조건: desiccated
• solubility: DMSO: 15 mg/mL; H₂O: slightly soluble
• 저장 온도: 2-8°C
• SMILES string: CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
• InChI: 1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
• InChI key: YNZFFALZMRAPHQ-SYYKKAFVSA-N
• 유전자 정보: human ... CNR1(1268) , CNR2(1269) ; rat ... Cnr1(25248)

설명

애플리케이션

CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).

생화학적/생리학적 작용

CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.

CP-55940 is a selective cannabinoid receptor agonist.

특징 및 장점

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H336
• 예방조치 성명서: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Hazard Classifications: STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)