A6226

AM251

>98% (HPLC), solid, cannabinoid receptor (CB1) antagonist

• 동의어(들): 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
• 실험식(Hill 표기법): C₂₂H₂₁N₄OCl₂I
• CAS Number: 183232-66-8
• Molecular Weight: 555.24
• MDL number: MFCD01861181
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24891069
• NACRES: NA.77

속성

• product name: AM251, >98% (HPLC), solid
• Quality Level: 100
• 분석: >98% (HPLC)
• 형태: solid
• 색상: white
• solubility: DMSO: >10 mg/mL; H₂O: insoluble
• 주관자: Sanofi Aventis
• SMILES string: Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(I)cc3)C(=O)NN4CCCCC4
• InChI: 1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
• InChI key: BUZAJRPLUGXRAB-UHFFFAOYSA-N
• 유전자 정보: mouse ... Cnr1(12801) , Cnr2(12802) ; rat ... Cnr1(25248)

설명

애플리케이션

AM251, a CB₁ cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.

생화학적/생리학적 작용

AM251 is a CB₁ cannabinoid receptor antagonist.

특징 및 장점

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

기타 정보

Salt content may vary.

안전성 정보

• 유해 및 위험 성명서: H413
• 예방조치 성명서: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves