A2729

Amisulpride

≥98% (HPLC)

• 동의어(들): 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide, DAN-2163, Deniban
• 실험식(Hill 표기법): C₁₇H₂₇N₃O₄S
• CAS Number: 71675-85-9
• Molecular Weight: 369.48
• EC Number: 275-831-7
• MDL number: MFCD00866691
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24890689
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated; protect from light
• 색상: white
• 주관자: Sanofi Aventis
• 저장 온도: 2-8°C
• SMILES string: O=C(NCC1CCCN1CC)C2=CC(S(=O)(CC)=O)=C(N)C=C2OC
• InChI: 1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
• InChI key: NTJOBXMMWNYJFB-UHFFFAOYSA-N
• 유전자 정보: human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR6(3362) , HTR7(3363)

설명

애플리케이션

Amisulpride has been used as a dopamine receptor inhibitor to study its effects on diabetic bone abnormalities in mice.

생화학적/생리학적 작용

Amisulpride is a substituted benzamide derivative. It has a higher affinity towards dopamine receptors in limbic structures than the striatal structures. Amisulpride has a therapeutic effect against schizophrenia.

Amisulpride is a highly selective D₂/D₃ dopamine receptor antagonist and atypical antipsychotic.

특징 및 장점

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves