SML0245

Candesartan cilexetil

≥98% (HPLC)

• 동의어(들): 2-ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, TCV 116, TCY 116
• 실험식(Hill 표기법): C₃₃H₃₄N₆O₆
• CAS Number: 145040-37-5
• Molecular Weight: 610.66
• MDL number: MFCD00871371
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825255
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: ≥15 mg/mL
• 주관자: Takeda
• 저장 온도: 2-8°C
• SMILES string: CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc4ccc(cc4)-c5ccccc5-c6nnn[nH]6
• InChI: 1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38)
• InChI key: GHOSNRCGJFBJIB-UHFFFAOYSA-N
• 유전자 정보: human ... AGTR1(185)

설명

생화학적/생리학적 작용

Candesartan cilexetil is a non-peptide angiotensin (AT2) receptor antagonist.

Candesartan cilexetil is the prodrug form of the potent angiotensin II receptor antagonist, candesartan. The prodrug is cleaved by esterases within the intestine to liberate the active molecule.

특징 및 장점

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360D,H373
• 예방조치 성명서: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2 Oral
• 표적 기관: Kidney,Blood
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable