RDD029

Guanidine thiocyanate

for molecular biology, free-flowing, Redi-Dri^™, ≥99.0%

• 동의어(들): GTC, Guanidine isothiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate
• Linear Formula: NH₂C(=NH)NH₂ · HSCN
• CAS Number: 593-84-0
• Molecular Weight: 118.16
• Beilstein: 3563461
• MDL number: MFCD00013027
• UNSPSC 코드: 12352107
• NACRES: NA.28

속성

• 제품 라인: Redi-Dri^™
• Quality Level: 100
• 분석: ≥99.0%
• 품질: for molecular biology; free-flowing
• mp: 120-122 °C (lit.)
• 외래 활성: DNAse, none detected; RNAse, none detected
• SMILES string: SC#N.NC(N)=N
• InChI: 1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
• InChI key: ZJYYHGLJYGJLLN-UHFFFAOYSA-N

설명

일반 설명

Guanadine thiocyanate (GTC) is a chaotropic agent and strong denaturant that is used in research for protein degredation in vitro. This is useful for DNA or RNA isolation and purification. GTC is a key reagent for inactivation of endogenous DNases and RNase for molecular biology techniques used to isolate nucliec acids from tissues, cells, or viral genomes.

애플리케이션

Guanidine thiocyanate is commonly used for research:

• to denature proteins in cell lysis buffer
• to isolate and purify RNA from cells and tissues
• to extract DNA from cellular and viral genomes

Chaotropic agent and strong denaturant; solubilizes cells.

생화학적/생리학적 작용

Guanadine thiocyanate is strong protein denaturant commonly combinded with phenol to lyse tissues, cells, and proteins during RNA isolation assay.

특징 및 장점

• Redi-Dri^™ makes working with hygroscopic chemicals easier
• Controls moisture and powder remains free-flowing
• Safer to handle and weigh out for routine use in lab
• Eliminates clumps and maintains product moisture and quality attributes

기타 정보

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법적 정보

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302 + H312 + H332,H314,H412
• 예방조치 성명서: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C
• 보충제 위험성: EUH032
• Storage Class Code: 8B - Non-combustible corrosive hazardous materials
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable