4995

Ouabain octahydrate

≥95% (HPLC), solid, Na⁺,K⁺-ATPase inhibitor, Calbiochem^®

• 동의어(들): Ouabain, Octahydrate, Strophanthin G
• 실험식(Hill 표기법): C₂₉H₄₄O₁₂ · 8H₂O
• CAS Number: 11018-89-6
• Molecular Weight: 728.77
• MDL number: MFCD00149240
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• product name: Ouabain, Octahydrate, Inhibits Na⁺,K⁺-ATPase.
• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white to off-white
• solubility: hot water: 10 mg/mL; room-temperature water: insoluble
• 배송 상태: ambient
• 저장 온도: 2-8°C
• InChI: 1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13?,15-,16+,17?,18+,19+,21+,22?,23?,24?,25?,26?,27?,28?,29?;;;;;;;;/m0......../s1
• InChI key: TYBARJRCFHUHSN-HMNHGHQSSA-N

설명

일반 설명

Inhibits Na⁺ and K⁺-dependent ATPases. Has cardiotonic properties.

Inhibits Na⁺,K⁺-ATPase. Exhibits cardiotonic properties. Preferentially enhances radiotoxicity in tumor cells and induces apoptosis by prolonging the irradiation-induced G₂ delay.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Na⁺,K⁺-ATPase

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Toxic (F)

재구성

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 2 months at -20°C.

기타 정보

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Verheye-Dua, F.A., and Bohm, L. 2000. Strahlenther Onkol. 176, 186.
Hasenauer, J., et al. 1993. J. Biol. Chem.268, 3289.
Rakowski, F.F. 1993. J. Gen. Physiol.101, 117.
Mahaney, J.E., and Grisham, C.M. 1992. Biochemistry31, 2025.
Xu, Z.J., et al. 1992. J. Physiol.456, 405.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H300,H331,H373
• 예방조치 성명서: P260 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 1 Oral - Acute Tox. 3 Inhalation - STOT RE 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3