368059-M

Granzyme B Substrate II, Fluorogenic

A fluorogenic substrate for the detection of granzyme B and caspase-8 activity.

• 동의어(들): Granzyme B Substrate II, Fluorogenic, Z-IETD-AFC, Caspase-8 Substrate II
• 실험식(Hill 표기법): C₃₇H₄₂F₃N₅O₁₃
• Molecular Weight: 821.75
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white
• solubility: DMSO: 1 mg/mL
• 형광: λ_ex ~400 nm; λ_em ~505 nm
• 저장 온도: −20°C

설명

일반 설명

A fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).

생화학적/생리학적 작용

Primary Target
Fluorogenic substrate for the detection of granzyme B and caspase-8 activity

경고

Toxicity: Standard Handling (A)

서열

Z-Ile-Glu-Thr-Asp-AFC

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

기타 정보

Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable