218773

Caspase-8 Inhibitor I, Cell-Permeable

The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.

• 동의어(들): Caspase-8 Inhibitor I, Cell-Permeable, Granzyme B Inhibitor II, Cell-permeable, IETD-CHO, Cell-permeable
• 실험식(Hill 표기법): C₉₅H₁₆₂N₂₀O₂₆
• Molecular Weight: 2000.42
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: DMSO: 5 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A potent, cell-permeable, and reversible inhibitor of caspase-8 and Granzyme B. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.

Potent, cell-permeable and reversible inhibitor of caspase-8 and Granzyme B.

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
caspase-8

Product does not compete with ATP.

Reversible: yes

경고

Toxicity: Standard Handling (A)

서열

Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Hamada, E., et al. 1990. J. Hepatol. 30, 807.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable