368056

Granzyme B Inhibitor IV

The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

• 동의어(들): Granzyme B Inhibitor IV, Ac-IEPD-CHO, Caspase-8 inhibitor III
• 실험식(Hill 표기법): C₂₂H₃₄N₄O₉
• Molecular Weight: 498.53
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: DMSO: 5 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A reversible inhibitor of Granzyme B that also inhibits caspase-8. Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes.

A reversible inhibitor of granzyme B and caspase-8.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
granzyme B

Product does not compete with ATP.

Reversible: yes

경고

Toxicity: Standard Handling (A)

서열

Ac-Ile-Glu-Pro-Asp-CHO

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem.272, 17907.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable