추천 제품
분석
>99% (TLC)
형태
powder
포장
pkg of 1 × 5 mg (700002P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand
배송 상태
dry ice
저장 온도
−20°C
InChI
1S/C27H39F7O/c1-16(5-4-12-25(28,26(29,30)31)27(32,33)34)20-8-9-21-19-7-6-17-15-18(35)10-13-23(17,2)22(19)11-14-24(20,21)3/h6,16,18-22,35H,4-5,7-15H2,1-3H3/t16-,18+,19+,20-,21+,22+,23+,24-/m1/s1
InChI key
DUAIJEYNEJQOCE-OLSVQSNTSA-N
일반 설명
F7-Cholesterol is a fluorinated derivative of cholesterol. It is a cholesterol analog. F7-Cholesterol is useful as helper lipid in conjunction with vectors for DNA transfection.
애플리케이션
F7-Cholesterol has been used:
- in the preparation of liposomes for DNA delivery studies
- to investigate its rescue functionality in hedgehog signaling in sterol-depleted cells
- in preparation of monolayers for pressure and area isotherms studies
생화학적/생리학적 작용
F7-Cholesterol has potential biological applications. It has a negative dipole moment. F7-Cholesterol rescues hedgehog signaling in sterol-depleted cells. The molecular orientation and phospholipid interaction of F7-cholesterol is similar to hydrogenated cholesterol.
포장
5 mL Amber Glass Screw Cap Vial (700002P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Langmuir monolayers of monocationic lipid mixed with cholesterol or fluorocholesterol: DNA adsorption studies
Paiva D, et al.
Langmuir, 29(6), 1920-1925 (2013)
Fluorocholesterols, in contrast to hydroxycholesterols, exhibit interfacial properties similar to cholesterol
Kauffman JM, et al.
Journal of Lipid Research, 41(6), 991-1003 (2000)
The effect of a fluorinated cholesterol derivative on the stability and physical properties of cationic DNA vectors
Paiva D, et al.
Soft Matter, 9(2), 401-409 (2013)
Synthesis of deuterium-and tritium-labeled 25, 26, 26, 26, 27, 27, 27-heptafluorocholesterol
Su X, et al.
Journal of Labelled Compounds, 42(6), 509-518 (1999)
Cholesterol-binding site of the influenza M2 protein in lipid bilayers from solid-state NMR
Elkins MR, et al.
Proceedings of the National Academy of Sciences of the USA, 114(49), 12946-12951 (2017)
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