900831

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

• 동의어(들): Carboxyl diazirine alkyne, Probe building block
• 실험식(Hill 표기법): C₈H₁₀N₂O₂
• CAS Number: 1450754-37-6
• Molecular Weight: 166.18
• MDL number: MFCD31433997
• UNSPSC 코드: 12352106

속성

• 양식: liquid
• Quality Level: 100
• 반응 적합성: reaction type: click chemistry
• 재고 정보: available only in USA
• 저장 온도: −20°C
• SMILES string: C#CCCC1(N=N1)CCC(O)=O
• InChI: 1S/C8H10N2O2/c1-2-3-5-8(9-10-8)6-4-7(11)12/h1H,3-6H2,(H,11,12)
• InChI key: JRNSKSYASHYNCM-UHFFFAOYSA-N

설명

애플리케이션

Used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein

Technology Spotlight: Trifuctional Probe Building Blocks

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable