900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 동의어(들): Bromo sulfonyl fluoride alkyne, Probe building block
• 실험식(Hill 표기법): C₁₂H₁₄BrFO₂SSi
• CAS Number: 2088829-12-1
• Molecular Weight: 349.29
• MDL number: MFCD30737997
• UNSPSC 코드: 12352200
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: solid
• 반응 적합성: reaction type: click chemistry
• 저장 온도: −20°C
• SMILES string: [Si](C)(C)(C)C#Cc1cc(cc(c1)CBr)[S](=O)(=O)F
• InChI: 1S/C12H14BrFO2SSi/c1-18(2,3)5-4-10-6-11(9-13)8-12(7-10)17(14,15)16/h6-8H,9H2,1-3H3
• InChI key: QSYGHPYMWBAJRL-UHFFFAOYSA-N

설명

애플리케이션

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable