900848

4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

• 동의어(들): Amino sulfonyl fluoride TMS-alkyne, Probe building block
• 실험식(Hill 표기법): C₁₁H₁₄FNO₂SSi
• CAS Number: 2088828-95-7
• Molecular Weight: 271.38
• UNSPSC 코드: 12352200
• NACRES: NA.22

속성

• 형태: liquid
• 재고 정보: available only in USA
• 저장 온도: −20°C
• SMILES string: NC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

설명

애플리케이션

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable