860794
Z-L-Phe chloromethyl ketone
98%
동의어(들):
N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone, NSC 251810, SL-01, ZPCK
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
Linear Formula:
C6H5CH2CH(NHCO2CH2C6H5)COCH2Cl
CAS Number:
Molecular Weight:
331.79
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Quality Level
분석
98%
양식
powder
광학 활성
[α]23/D +30°, c = 1 in chloroform
반응 적합성
reaction type: solution phase peptide synthesis
mp
107-108 °C (lit.)
응용 분야
peptide synthesis
저장 온도
−20°C
SMILES string
ClCC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2
InChI
1S/C18H18ClNO3/c19-12-17(21)16(11-14-7-3-1-4-8-14)20-18(22)23-13-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,22)/t16-/m0/s1
InChI key
OYHLRJGDELITAF-INIZCTEOSA-N
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애플리케이션
Enzyme inhibitor.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Biogenesis of vaccina: interrelationship between post-translational cleavage, virus assembly, and maturation.
M Silver et al.
Virology, 117(2), 341-356 (1982-03-01)
T Wileman et al.
Cell regulation, 2(9), 753-765 (1991-09-01)
The endoplasmic reticulum, or an organelle closely associated with it, contains proteases that can be used to remove partially assembled or improperly folded proteins. Very little is known at present about the types of protease that degrade these proteins. The
G Jung et al.
Protein science : a publication of the Protein Society, 4(11), 2433-2435 (1995-11-01)
The essential histidine residue of carboxypeptidase Y (CPY) was modified by a site-specific reagent, a chloromethylketone derivative of benzyloxycarbonyl-L-phenylalanine. The single modified histidine residue was converted to N tau-carboxy-methyl histidine (cmHis) upon performic acid oxidation. A peptide containing cmHis was
Inhibition of carboxypeptidase Y by chloromethyl ketone derivatives of benzyloxycarbonyl-L-phenylalanine.
R Hayashi et al.
Journal of biochemistry, 76(6), 1355-1357 (1974-12-01)
J Brtko et al.
Endocrine regulations, 26(3), 127-131 (1992-09-01)
The effect of protease inhibitors N-tosyl-L-phenylalanine chloromethyl ketone (TPCK) and N-carbobenzoxy-L-phenylalanine chloromethyl ketone (ZPCK) at concentrations ranging from 1.5 x 10(-6) mol/l to 1.5 x 10(-4) mol/l on the specific binding of 3,5,3'-triiodothyronine (T3) to rat liver nuclear receptors was
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