449458

(tert-Butyldimethylsilyloxy)acetaldehyde

90%

• 동의어(들): (tert-Butyldimethylsiloxy)acetaldehyde, 2-(tert-Butyldimethylsilyloxy)acetaldehyde, 2-[(tert-Butyl)dimethylsiloxy]acetaldehyde, 2-[(tert-Butyldimethylsilanyl)oxy]acetaldehyde, 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]acetaldehyde, Dimethyl-tert-butylsilyloxyacetaldehyde
• Linear Formula: (CH₃)₃CSi(CH₃)₂OCH₂CHO
• CAS Number: 102191-92-4
• Molecular Weight: 174.31
• MDL number: MFCD01321229
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24868481
• NACRES: NA.22

속성

• 분석: 90%
• refractive index: n20/D 1.432 (lit.)
• bp: 165-167 °C (lit.)
• density: 0.915 g/mL at 25 °C (lit.)
• 작용기: aldehyde
• 저장 온도: 2-8°C
• SMILES string: CC(C)(C)[Si](C)(C)OCC=O
• InChI: 1S/C8H18O2Si/c1-8(2,3)11(4,5)10-7-6-9/h6H,7H2,1-5H3
• InChI key: MEBFFOKESLAUSJ-UHFFFAOYSA-N

설명

애플리케이션

(tert-Butyldimethylsilyloxy)acetaldehyde is a versatile reagent commonly used in synthetic glycobiology. It can act both as an aldol donor and an aldol acceptor in the stereocontrolled production of erythrose. It is used as an important reagent in the total synthesis of (+)-ambruticin, (−)-laulimalide, (−)-salinosporamide A, and (+)-leucascandrolide A.

Employed in the construction of the key tetrahydropyran subunit in a recent synthesis of the marine natural product (–)-dactylodide.

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H226,H315,H319,H335
• 예방조치 성명서: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 140.0 °F - closed cup
• Flash Point (°C): 60 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter