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Merck
모든 사진(1)

주요 문서

440736

Sigma-Aldrich

4-Thiouracil

97%

동의어(들):

2-Hydroxy-4-mercaptopyrimidine

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About This Item

실험식(Hill 표기법):
C4H4N2OS
CAS Number:
Molecular Weight:
128.15
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

양식

powder

mp

295 °C (dec.) (lit.)

solubility

1 M NaOH: soluble 50 mg/mL

SMILES string

Oc1nccc(S)n1

InChI

1S/C4H4N2OS/c7-4-5-2-1-3(8)6-4/h1-2H,(H2,5,6,7,8)

InChI key

OVONXEQGWXGFJD-UHFFFAOYSA-N

애플리케이션

4-Thiouracil is suitable reagent employed in Schneider′s media for the embryos during RNA extraction. It may be employed as reagent for the Northwestern blotting technique.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

Structure and tautomerism of the neutral and monoanionic forms of 4-thiouracil derivatives.
A Psoda et al.
Journal of the American Chemical Society, 96(22), 6832-6839 (1974-10-30)
Michael R Miller et al.
Nature methods, 6(6), 439-441 (2009-05-12)
We found that the combination of spatially restricted uracil phosphoribosyltransferase (UPRT) expression with 4-thiouracil delivery can be used to label and purify cell type-specific RNA from intact complex tissues in Drosophila melanogaster. This method is useful for isolating RNA from
Jeanine S Morey et al.
PloS one, 8(6), e66347-e66347 (2013-06-19)
Dinoflagellates possess many physiological processes that appear to be under post-transcriptional control. However, the extent to which their genes are regulated post-transcriptionally remains unresolved. To gain insight into the roles of differential mRNA stability and de novo transcription in dinoflagellates
P J Unrau et al.
Nature, 395(6699), 260-263 (1998-09-29)
The 'RNA world' hypothesis proposes that early life developed by making use of RNA molecules, rather than proteins, to catalyse the synthesis of important biological molecules. It is thought, however, that the nucleotides constituting RNA were scarce on early Earth.
Xiaoran Zou et al.
The journal of physical chemistry. B, 118(22), 5864-5872 (2014-05-14)
Intensified research interests are posed with the thionucleobase 4-thiouracil (4-TU), due to its important biological function as site-specific photoprobe to detect RNA structures and nucleic acid-nucleic acid contacts. By means of time-resolved IR spectroscopy and density functional theory (DFT) studies

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