추천 제품
생물학적 소스
synthetic (organic)
Quality Level
제품 라인
BioReagent
분석
≥99%
양식
powder
기술
cell culture | mammalian: suitable
mp
163-167 °C (lit.)
solubility
H2O: 50 mg/mL
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI key
DRTQHJPVMGBUCF-XVFCMESISA-N
유전자 정보
mouse ... Uck1(22245)
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일반 설명
Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is a substrate for nucleotide synthesis in living organisms by de- novo and salvage pathways.
애플리케이션
Uridine has been used:
- as an inhibitor of schwann cell proliferation in rat dorsal root ganglia (DRG) neurons culture
- as a medium supplement for epiblasts culture
- as a component of 5-fluoro-2′-deoxyuridine stock solution used for neuronal culture
생화학적/생리학적 작용
Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like, treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine induces insulin resistance.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Preparation of rat brain aggregate cultures for neuron and glia development studies
Journal of Visualized Experiments, 22(31), 625-633 (2009)
Characterisation of bovine epiblast-derived outgrowth colonies
Reproduction, Fertility, and Development, 22(4), 625-633 (2010)
Biochemistry of uridine in plasma
Clinica Chimica Acta; International Journal of Clinical Chemistry, 412(19-20), 17121724-17121724 (2011)
Neurite outgrowth of dorsal root ganglia neurons is enhanced on aligned nanofibrous biopolymer scaffold with carbon nanotube coating
Neuroscience Letters, 501(1), 10-14 (2011)
CAD mutations and uridine-responsive epileptic encephalopathy
Brain, 140(2), 279286-279286 (2016)
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