U3750

Uridine

≥99%

• 동의어(들): 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• 실험식(Hill 표기법): C₉H₁₂N₂O₆
• CAS Number: 58-96-8
• Molecular Weight: 244.20
• Beilstein: 754902
• EC Number: 200-407-5
• MDL number: MFCD00006526
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24900640
• NACRES: NA.51

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥99%
• 형태: powder
• mp: 163-167 °C (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
• InChI key: DRTQHJPVMGBUCF-XVFCMESISA-N
• 유전자 정보: mouse ... Uck1(22245)

설명

일반 설명

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

애플리케이션

Uridine has been used:

• as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
• in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
• in chase sequencing experiments

생화학적/생리학적 작용

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)