417556

4-Fluorophenylboronic acid

≥95%

• 동의어(들): (4-Fluorophenyl)boric acid, (4-Fluorophenyl)dihydroxyborane, (4-Fluorophenyl)dihydroxyboron, (p-Fluorophenyl)boric acid, 4-Fluorobenzeneboronic acid, p-Fluorobenzylboronic acid, p-Fluorophenylboronic acid, NSC 142683
• Linear Formula: FC₆H₄B(OH)₂
• CAS Number: 1765-93-1
• Molecular Weight: 139.92
• Beilstein: 2829653
• MDL number: MFCD00039136
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24866160
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: powder
• mp: 262-265 °C (lit.)
• 작용기: fluoro
• SMILES string: OB(O)c1ccc(F)cc1
• InChI: 1S/C6H6BFO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
• InChI key: LBUNNMJLXWQQBY-UHFFFAOYSA-N

설명

애플리케이션

4-Fluorophenylboronic acid can be used as a reactant in coupling reactions with arenediazonium tetrafluoroborates, iodonium salts, and iodanes. It is also used to make novel biologically active terphenyls.

It can also be used as a reactant in:

• Suzuki coupling using microwave and triton B catalyst.
• Pd-catalyzed direct arylation of pyrazoles with phenylboronic acids.
• Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles.
• Cu-catalyzed Petasis reactions.
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence.
• Ruthenium catalyzed direct arylation.
• Rh-catalyzed asymmetric conjugate additions.
• Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids.
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions.
• Suzuki cross-coupling of tetrabromothiophene.
• Palladium-catalyzed addition to nitriles.

기타 정보

Contains varying amounts of anhydride

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves