394963

N,N-Dimethylformamide dimethyl acetal

for GC derivatization, LiChropur^™

• 동의어(들): 1,1-Dimethoxy-N,N-dimethylmethylamine, 1,1-Dimethoxytrimethylamine
• Linear Formula: (CH₃)₂NCH(OCH₃)₂
• CAS Number: 4637-24-5
• Molecular Weight: 119.16
• Beilstein: 506020
• EC Number: 225-063-3
• MDL number: MFCD00008482
• UNSPSC 코드: 12000000
• PubChem Substance ID: 24864631
• NACRES: NA.22

속성

• Grade: derivatization grade ((GC derivatization)); for GC derivatization
• 분석: >95%
• 양식: liquid
• 품질: LiChropur^™
• 반응 적합성: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• 기술: gas chromatography (GC): suitable
• refractive index: n20/D 1.396 (lit.)
• bp: 102-103 °C/720 mmHg (lit.)
• density: 0.897 g/mL at 25 °C (lit.)
• SMILES string: COC(OC)N(C)C
• InChI: 1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3
• InChI key: ZSXGLVDWWRXATF-UHFFFAOYSA-N

설명

일반 설명

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.

애플리케이션

It may be used in methylation of heterocyclic compounds which contains SH, NH, OH groups such as benzimidazole, naphth[2,3-c]imidazole, imidazo[4,5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo[4,3-b]pyridazine. It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation.

Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid.

Used in the preparation of formamidine derivatives, which are synthetic intermediates.

Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.

기타 정보

Reagent for n-dimethylaminomethylene and methyl esters.

법적 정보

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H317,H318,H332
• 예방조치 성명서: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Sens. 1
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 42.8 °F
• Flash Point (°C): 6 °C
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter