392731

(DHQD)₂PHAL

≥95%

• 동의어(들): Hydroquinidine 1,4-phthalazinediyl diether
• 실험식(Hill 표기법): C₄₈H₅₄N₆O₄
• CAS Number: 140853-10-7
• Molecular Weight: 778.98
• Beilstein: 5475678
• MDL number: MFCD00198107
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24864481
• NACRES: NA.22

속성

• 분석: ≥95%
• 형태: powder
• 광학 활성: [α]22/D −262°, c = 1.2 in methanol
• 환경친화적 대안 제품 점수: old score: 5; new score: 3; Find out more about DOZN™ Scoring
• 환경친화적 대안 제품 특성: Waste Prevention; Less Hazardous Chemical Syntheses; Safer Solvents and Auxiliaries; Inherently Safer Chemistry for Accident Prevention; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 160 °C (dec.) (lit.)
• 환경친화적 대안 카테고리: , Re-engineered
• SMILES string: CC[C@H]1CN2CCC1CC2[C@@H](Oc3nnc(O[C@H](C4CC5CCN4C[C@@H]5CC)c6ccnc7ccc(OC)cc67)c8ccccc38)c9ccnc%10ccc(OC)cc9%10
• InChI: 1S/C48H54N6O4/c1-5-29-27-53-21-17-31(29)23-43(53)45(35-15-19-49-41-13-11-33(55-3)25-39(35)41)57-47-37-9-7-8-10-38(37)48(52-51-47)58-46(44-24-32-18-22-54(44)28-30(32)6-2)36-16-20-50-42-14-12-34(56-4)26-40(36)42/h7-16,19-20,25-26,29-32,43-46H,5-6,17-18,21-24,27-28H2,1-4H3/t29-,30-,31-,32-,43+,44+,45-,46-/m0/s1
• InChI key: YUCBLVFHJWOYDN-HVLQGHBFSA-N

설명

일반 설명

(DHQD)₂PHAL is a dimer that can be used as a chiral amine catalyst for asymmetric halogenations.

(DHQD)₂PHAL is a modified cinchona alkaloid derivative mainly used as a ligand for enantioselective catalysis.

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Less Hazardous Chemical Syntheses”, "Safer Solvents and Auxiliaries" and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard.

애플리케이션

(DHQD)₂PHAL may be used as ligand for:

• Osmium trioxide catalyzed asymmetric dihydroxylation of olefins.
• Palladium catalyzed Suzuki-Miyaura coupling of aryl/heteroaryl halides with aryl boronic acids in aqueous medium and in the absence of phosphine/organic solvent.
• Copper(I)-catalyzed azide-alkyne cycloaddition reaction to synthesize 1,2,3-triazoles in water.

Hydroquinidine 1,4-phthalazinediyl diether [(DHQD)₂PHAL] can be used:

• As a ligand for Sharpless asymmetric dihydroxylation.
• For enantioselective α-fluorination of carbonyl compounds.

법적 정보

Sold under license from Rhodia Pharma Solutions.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)