1133977

Cinacalcet hydrochloride

United States Pharmacopeia (USP) Reference Standard

• 別名: AMG 073 hydrochloride, KRN 1493 hydrochloride, N-[1-(R)-(-)-(1-naphthyl)ethyl]-3-[3(trifluoromethyl)phenyl]-1-aminopropane hydrochloride, NPS 1493 hydrochloride
• 実験式（ヒル表記法）: C₂₂H₂₂F₃N·HCl
• CAS番号: 364782-34-3
• 分子量: 393.87
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: cinacalcet
• メーカー／製品名: USP
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• InChI: 1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1
• InChI Key: QANQWUQOEJZMLL-PKLMIRHRSA-N

詳細

詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

Cinacalcet hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生物化学的／生理学的作用

Cinacalcet is a positive allosteric modulator of the Calcium Sensing Receptor (CaSR) that acts as a calcimimetic. It increases the sensitivity of the calcium-sensing receptor to extracellular calcium resulting in a decrease in serum calcium levels.

その他情報

Sales restrictions may apply.

安全性情報

• ピクトグラム: GHS05,GHS07,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302 - H314 - H317 - H373 - H413
• 注意書き: P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P314
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1B - STOT RE 2
• ターゲットの組織: eye - retina
• 保管分類コード: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable