1096724

カルムスチン

United States Pharmacopeia (USP) Reference Standard

• 別名: 1,3-ビス(2-クロロエチル)-1-ニトロソ尿素, BCNU
• 実験式（ヒル表記法）: C₅H₉Cl₂N₃O₂
• CAS番号: 154-93-8
• 分子量: 214.05
• MDL番号: MFCD00057706
• UNSPSCコード: 41116107
• PubChem Substance ID: 329749246
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: carmustine
• 形状: (Oily liquid to amorphous solid)
• メーカー／製品名: USP
• mp: 30 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: −20°C
• SMILES記法: ClCCNC(=O)N(CCCl)N=O
• InChI: 1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
• InChI Key: DLGOEMSEDOSKAD-UHFFFAOYSA-N
• 遺伝子情報: human ... GSR(2936)

詳細

詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

• Enhancing glioblastoma treatment: Overexpression of Let-7a-3p in U87MG glioblastoma cells enhances chemosensitivity to Carmustine, promoting autophagy and suppressing cell survival, suggesting its role in improving outcomes in glioblastoma multiforme treatment using antineoplastic alkylating compounds (Bahojb Mahdavi et al., 2024).


• Pharmacogenomic profiling in renal cancer: Characterization of mitoribosomal small subunit genes in renal cell carcinoma reveals significant implications for Carmustine′s pharmacogenomic interaction, enhancing understanding of its mechanism in cancer therapy and providing a basis for personalized treatment approaches (Wei et al., 2024).

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

その他情報

Sales restrictions may apply.

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H300,H350,H360
• 注意書き: P201 - P280 - P301 + P330 + P331 + P310 - P308 + P313
• 危険有害性の分類: Acute Tox. 2 Oral - Carc. 1B - Repr. 1B
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable