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Merck

821455

TSKgel® 逆相 HPLC カラム (シリカベース)

phase C18 (octadecyl), L × I.D. 15 cm × 4.6 mm, 5 μm particle size

別名:

TSKgel® Reversed Phase HPLC Column

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About This Item

UNSPSCコード:
41115711
eCl@ss:
32110501

物質

stainless steel hardware

認証

suitable for USP L1

製品種目

TSKgel®

メーカー/製品名

Tosoh ODS-100V, 21455

標識化の程度

15% Carbon, endcapped with bifunctional dialkylsilane

パラメーター

0-100% organic solvent
1.0 mL/min standard flow rate
10-50 °C temperature
180 bar max. pressure

テクニック

HPLC: suitable

L × 内径

15 cm × 4.6 mm

表面積

450 m2/g

マトリックス

silica particle platform

マトリックス活性基

C18 (octadecyl) phase

粒径

5 μm

ポアサイズ

100 Å

使用pH

2.0-7.5

分離法

reversed phase

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詳細

TSKgel® ODS-100V and TSKgel ODS-100Z columns incorporate the best-in-class surface properties to limit secondary interactions of basic, acidic and chelating compounds. Take advantage of the benefits of high column efficiency and symmetrical peak shapes to reduce your analysis and method development time! The ultra high purity Type B base silica contains negligible amounts of metal ion impurities. Combined with monomeric bonding chemistry, this silica makes the best general purpose Reversed Phase columns suitable for the most demanding separations in quality control as well as in research and development. TSKgel ODS-100V columns have a lower carbon content than ODS-100Z columns, making the bonded phase surface 100% water wettable and the preferred choice to retain polar metabolites.

アプリケーション

TSKgel® ODS-100V HPLC Column may be used for the separation of:
  • Docetaxel in human plasma during its determination by high performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS) combined with electrospray ionization (ESI) and multiple reaction monitoring (MRM) detection.
  • Constituents of Chinese medicine Niu Huang Jie Du Pill during their analysis by HPLC combined with diode array detection (DAD).
  • Organic and inorganic selenium in diet supplements during the determination using HPLC-ESI-MS/MS with MRM detection.
  • Estrogenic compounds 8-prenylnaringenin, zearalenone, α- and β-zearalenol in beer during their identification using LC-ESI-MS with single ion monitoring (SIM) detection.
  • Lincomycin, spectinomycin and its impurities in pharmaceutical products during their analysis by HPLC combined with charged aerosol detection (CAD) as well as HPLC coupled to time-of flight mass spectrometer (TOFMS) with ESI.

物理的形状

Shipped in acetonitrile.

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法的情報

TSKgel is a registered trademark of Tosoh Corporation

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試験成績書(COA)

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Development of high performance liquid chromatography methods with charged aerosol detection for the determination of lincomycin, spectinomycin and its impurities in pharmaceutical products
Stypulkowska K, et al.
Journal of Pharmaceutical and Biomedical Analysis, 112(1), 8-14 (2015)
Simultaneous quantitation and identification of organic and inorganic selenium in diet supplements by liquid chromatography with tandem mass spectrometry.
Zembrzuska J, et al.
Food Chemistry, 142(3), 178-187 (2014)
A rapid and sensitive LC/ESI-MS/MS method for quantitative analysis of docetaxel in human plasma and its application to a pharmacokinetic study.
Yamaguchi H, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 893, 157-161 (2012)
Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry
Liang X, et al.
Journal of Pharmaceutical and Biomedical Analysis, 51(3), 565-571 (2010)
Direct determination of the estrogenic compounds 8-prenylnaringenin, zearalenone, ?- and ?-zearalenol in beer by liquid chromatography-mass spectrometry.
Maragou NC, et al.
Journal of Chromatography A, 1202(1), 47-57 (2008)

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