Z4751

抗ザイキシン抗体 ウサギ宿主抗体

IgG fraction of antiserum, buffered aqueous solution

• 別名: Anti-ESP-2, Anti-HED-2
• MDL番号: MFCD01634364
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 82-84 kDa
• 交差性: mouse, human, rat
• テクニック: indirect immunofluorescence: 1:100 using Rat1 cells; western blot (chemiluminescent): 1:1,000 using whole extract of human HeLa cells; western blot (chemiluminescent): 1:2,000 using whole extract of mouse NIH3T3 cells
• UniProtアクセッション番号: Q15942
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ZYX(7791) ; mouse ... Zyx(22793) ; rat ... Zyx(114636)

詳細

詳細

Zyxin (ZYX ), a zinc-binding phosphoprotein of ∼61kDa is located at focal adhesions and along the actin cytoskeleton. It has three LIM domains. This structural protein is located on human chromosome 7q34.

免疫原

ヒトジキシンのアミノ酸134-150 (N末端システイン付加)に相当する合成ペプチドのKLH結合体。マウスでは相当する配列の内1個のアミノ酸が異なっています。

アプリケーション

Anti-Zyxin antibody has been used in fluorescence microscopy.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 papers)

生物化学的／生理学的作用

Zyxin (ZYX ) participates in the modulation of actin assembly at focal adhesions and stress fibers. It also regulates cell adhesion and cell cycle. Overexpression of ZYX is associated with melanoma. Suppression of ZYX  prevents cell growth.

物理的形状

0.01M PBS溶液(pH 7.4, 15mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)