V9014

Anti-VMAT2 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: 抗SLC18A2抗体, 抗SVAT抗体, 抗SVMT抗体, 抗VAT2抗体
• MDL番号: MFCD02097601
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 化学種の反応性: mouse, rat, human
• 濃度: ~1 mg/mL
• テクニック: immunohistochemistry: 1:100-1:250; western blot: 1:500-1:1,000
• UniProtアクセッション番号: Q05940
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SLC18A2(6571) ; mouse ... Slc18a2(214084) ; rat ... Slc18a2(25549)

詳細

詳細

Vesicular monoamine transporter 2 (VMAT2) , also known as solute carrier family 18 member A2 (SLC18A2), is a transmembrane protein that acts at nerve terminals. It is expressed in platelets and in central, peripheral and enteric neurons. The gene encoding VMAT2 consists of 16 exons and is mapped to human chromosome 10q25.

免疫原

synthetic peptide corresponding an internal sequence of human VMAT2. This sequence is identical in mouse and rat.

アプリケーション

Anti-VMAT2 antibody produced in rabbit has also been used in immunofluorescence.

Anti-VMAT2 antibody produced in rabbit has been used in western blot analysis.

生物化学的／生理学的作用

Vesicular monoamine transporter 2 (VMAT2) modulates the release of neurotransmitters like dopamine, serotonin and γ-amino butyric acid. It has a role in the accumulation of neurotransmitters in synaptic vesicles to prevent toxicity. VMAT2 has been linked to tardive dyskinesia and may be associated with Parkinson′s disease.

物理的形状

solution in phosphate buffered saline, containing 0.02% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)