T2019

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powder

• 別名: パラモルフィン
• 実験式（ヒル表記法）: C₁₉H₂₁NO₃
• CAS番号: 115-37-7
• 分子量: 311.37
• EC Number: 204-084-1
• MDL番号: MFCD00027409
• UNSPSCコード: 12352200
• PubChem Substance ID: 24900006
• NACRES: NA.77

特性

• 形状: powder
• 薬剤管理: USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 溶解性: alcohol: soluble 1 in 10 of alcohol; benzene: soluble 1 in 18 in benzene; chloroform: soluble 50 mg/ml, clear, yellow; diethyl ether: soluble 1 in 135 of ether; H₂O: insoluble
• SMILES記法: [H][C@@]12Oc3c(OC)ccc4C[C@H]5N(C)CC[C@]1(C5=CC=C2OC)c34
• InChI: 1S/C19H21NO3/c1-20-9-8-19-12-5-7-15(22-3)18(19)23-17-14(21-2)6-4-11(16(17)19)10-13(12)20/h4-7,13,18H,8-10H2,1-3H3/t13-,18+,19+/m1/s1
• InChI Key: FQXXSQDCDRQNQE-VMDGZTHMSA-N

詳細

アプリケーション

Thebaine has been used for the synthesis of neopinone/codeinone ring systems. Thebaine has also been used as a 1 mg/ml standard in methanol for urine thebaine analysis in individuals who had consumed poppy seeds.

生物化学的／生理学的作用

The (-)-isomer of thebaine is the naturally-occurring constituent of opium that is a precursor of morphine. It has poor antinociceptive activity and induces convulsions. It binds to μ and δ opioid receptors in vitro.

物理的形状

Alkaloid powder

調製ノート

Thebaine dissolves in chloroform at 50 mg/ml to yield a clear, yellow solution. It soluble in alcohol, ether, and benzene at 1:10, 1: 135, and 1:18 parts respectively. However, thebaine does not dissolve in water.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301
• 注意書き: P264 - P270 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges