T1450

Anti-γ-Tubulin (LL-17) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-γ-Tubulin (LL-17)
• MDL番号: MFCD06411816
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 48 kDa
• 化学種の反応性: Caenorhabditis elegans
• テクニック: western blot: 0.75-1.5 μg/mL using whole extract of C. elegans.
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: Caenorhabditis elegans ... Tbg-1(176361)

詳細

詳細

γ-Tubulin is a widely expressed and highly conserved protein within the microtubule organizing centers (MTOCs) or centrosome in eukaryotic cells. It is a member of the tubulin superfamily of proteins, which includes α and β tubulin and the newly discovered centrosomal-associated proteins, δ and ε tubulin. γ-Tubulin abundance is less than 1% of the level of either α or β tubulin.

免疫原

synthetic peptide corresponding to the C-terminus of C. elegans γ-tubulin (amino acids 428-444) with N-terminal added cysteine, conjugated to KLH. This sequence is highly specific for C. elegans γ-tubulin, and not found in γ-tubulin sequences of other species or other members of the tubulin family such as α-, β-, δ-, and ε-tubulins.

アプリケーション

Anti-γ-Tubulin (LL-17) antibody produced in rabbit has been used in immunoblotting.

生物化学的／生理学的作用

γ-Tubulin has an essential role in microtubule nucleation by the centrosomes. γ-Tubulin does not polymerize with α-tubulin/β-tubulin, but instead it is localized to the centrosome and to the cytoplasm. γ-Tubulin is found as part of a large protein complex containing at least five other proteins and has a shape of a ring (γ-tubulin ring complex, γ-TuRC) that is roughly the same diameter as a microtubule. γ-Tubulin binds the microtubule minus ends and is responsible for mediating the link between microtubules and the centrosome.

ターゲットの説明

γTubulin (LL-17) is a widely expressed and highly conservedprotein within the microtubule organizing centers (MTOCs) or centrosome in eukaryotic cells.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable