T122

Telenzepine dihydrochloride hydrate

solid, ≥98% (HPLC)

• 別名: 4,9-ジヒドロ-3-メチル-4-[(4-メチル-1-ピペラジニル)アセチル]-10H-チエノ[3,4-b][1,5]ベンゾジアゼピン-10-オン 二塩酸塩
• 実験式（ヒル表記法）: C₁₉H₂₂N₄O₂S · 2HCl · xH₂O
• CAS番号: 147416-96-4
• 分子量: 443.39 (anhydrous basis)
• MDL番号: MFCD11045947
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277875
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: solid
• 色: white
• 溶解性: H₂O: >10 mg/mL
• SMILES記法: O.Cl.Cl.CN1CCN(CC1)CC(=O)N2c3ccccc3NC(=O)c4csc(C)c24
• InChI: 1S/C19H22N4O2S.2ClH.H2O/c1-13-18-14(12-26-13)19(25)20-15-5-3-4-6-16(15)23(18)17(24)11-22-9-7-21(2)8-10-22;;;/h3-6,12H,7-11H2,1-2H3,(H,20,25);2*1H;1H2
• InChI Key: HZWCRPGARSMPNS-UHFFFAOYSA-N
• 遺伝子情報: human ... CHRM1(1128)

詳細

アプリケーション

Telenzepine dihydrochloride hydrate was used to study M₁ muscarinic receptor-mediated signaling in juvenile rat hippocampus and rat urinary bladder.

生物化学的／生理学的作用

Telenzepine is an analog of pirenzepine and inhibits the secretion of gastric acid. It is an antagonist to M₁-receptor and targets the oxyntic gastric glands and the salivary glands.

特徴および利点

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)