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由来生物
goat
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
lyophilized powder
化学種の反応性
mouse
テクニック
capture ELISA: suitable
flow cytometry: 5-25 μg/mL
indirect immunofluorescence: 15 μg/mL using mouse cells and tissues
neutralization: suitable
western blot: 0.1-0.2 μg/mL
UniProtアクセッション番号
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
mouse ... Tnf(21926)
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詳細
Tumor Necrosis Factor-α (TNF-α) is a protein produced by lipopolysaccharide-stimulated macrophages and causes tumor necrosis. It also facilitates many functions like stimulate growth of human fibroblasts and other cell lines, activate polymorphonuclear neutrophils and osteoclasts and collagenase production. Anti-Tumor Necrosis Factor-α antibody can be used for neutralizing the biological activity of recombinant mouse TNF-α. It can also be used in indirect immunofluorescence. Goat anti-Tumor Necrosis Factor-α antibody reacts specifically with recombinant mouse TNF-α.
特異性
組み換えﾏｳｽTNF-αの生物活性を中和する抗体です。
免疫原
組み換えマウスTNF-α
アプリケーション
Anti-Tumor Necrosis Factor-α antibody can be used in ELISA capture and flow cytometry. It can also be used in immunoblotting.
物理的形状
凍結乾燥品 (PBS溶液, 5%トレハロ-ス含有, 0.2μmフィルタ-濾過済み)。
調製ノート
マウスTNF-αアフィニティ-クロマトグラフィ-で精製されています。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
T0938-VAR:
T0938-.1MG-PW:
T0938-BULK:
T0938-.1MG:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
E A Carswell et al.
Proceedings of the National Academy of Sciences of the United States of America, 72(9), 3666-3670 (1975-09-01)
In studying "hemorrhagic necrosis" of tumors produced by endotoxin, it was found that the serum of bacillus Calmette--Guerin (BCG)-infected mice treated with endotoxin contains a substance (tumor necrosis factor; TNF) which mimics the tumor necrotic action of endotoxin itself. TNF-positive
D R Bertolini et al.
Nature, 319(6053), 516-518 (1986-02-06)
When leukocytes are exposed to mitogens or antigens in vitro, they release bone-resorbing activity into the culture supernatants which can be detected by bioassay. Like many lymphocyte-monocyte products, this activity has been difficult to purify because of its low abundance
J M Dayer et al.
The Journal of experimental medicine, 162(6), 2163-2168 (1985-12-01)
Cachectin/TNF (tumor necrosis factor), an endotoxin-induced murine macrophage hormone implicated in the pathogenesis of cachexia and shock, has been found capable of stimulating collagenase and prostaglandin E2 (PGE2) production by isolated human synovial cells and dermal fibroblasts. This bioactivity associated
B J Sugarman et al.
Science (New York, N.Y.), 230(4728), 943-945 (1985-11-22)
Modulation of the growth of human and murine cell lines in vitro by recombinant human tumor necrosis factor-alpha (rTNF-alpha) and recombinant human interferon-gamma (rIFN-gamma) was investigated. rTNF-alpha had cytostatic or cytolytic effects on only some tumor cell lines. When administered
Jianhua Liu et al.
Frontiers in physiology, 8, 611-611 (2017-10-11)
Objective: This study aimed to investigate the effect of osmotin on myocardial ischemia/reperfusion (I/R), as well as the underlying mechanisms. Methods:In vitro I/R injury model was established on rat cardiac myoblast H9c2 cells by oxygen and glucose deprivation followed by
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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