SRP8047

Omentin human

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• 別名: 内皮レクチンHL-1, 腸ラクトフェリン受容体
• CAS番号: 786735-12-4
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in CHO cells
• タグ: FLAG^® tagged
• アッセイ: >95% (SDS-PAGE)
• フォーム: lyophilized
• 分子量: ~38 kDa
• 包装: pkg of 10 μg
• 保管条件: avoid repeated freeze/thaw cycles
• テクニック: ligand binding assay: suitable
• 不純物: <0.1 EU/μg endotoxin, tested
• 色: white
• UniProtアクセッション番号: Q8WWA0
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... ITLN1(55600)

詳細

詳細

Omentin (intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. It is a plasma adipokine made up of 313 amino acids.

アプリケーション

Omentin (intelectin-1) has been used in intelectin binding and cleavage assays.

生物化学的／生理学的作用

Omentin (intelectin-1) has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases protein kinase B (AKT) phosphorylation in the absence and presence of insulin. Omentin was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues. It has anti-inflammatory and insulin-sensitizing properties. The protein may be a biomarker of metabolic disorders. It has been shown to be over-expressed in human malignant pleural mesothelioma (MPM).

物理的形状

凍結乾燥品(PBS)。

再構成

Reconstitute with 100 μL deionized water.

その他情報

Human omentin (aa 17-313) is fused at the N-terminus to a FLAG^®-tag.

法的情報

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable