SRP8010

GPX1 human

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

• 別名: Cellular glutathione peroxidase, Death receptor 6, GSHPx-1, Glutathione peroxidase 1
• CAS番号: 1451392-36-1
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• タグ: His tagged
• アッセイ: >90% (SDS-PAGE)
• フォーム: lyophilized
• 分子量: ~25 kDa by SDS-PAGE
• 包装: pkg of 10 μg
• 保管条件: avoid repeated freeze/thaw cycles
• 不純物: <1 EU/μg endotoxin, tested
• 色: white
• UniProtアクセッション番号: P07203
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... GPX1(2876)

詳細

詳細

GPX1 (glutathione peroxidase 1) is a selenoprotein and the gene is mapped to human chromosome 3p21.3. It is present in the cytoplasm and is widely expressed.

生物化学的／生理学的作用

GPX1 (glutathione peroxidase 1) is responsible for scavenging free radicals and derivatives. GPXs reduces lipid hydroperoxides to the corresponding alcohols as well as free hydrogen peroxide to water. Mutations in the GPX1 gene are associated with nonalcoholic fatty liver disease (NAFLD) susceptibility. Mutation in GPX1 at C594T is linked with oxidative stress-associated disorders, including prostate cancer and bladder cancer.

物理的形状

Lyophilized from 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl, 1 mM DTT.

再構成

Reconstitute with 100 μL deionized water.

その他情報

Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable