SRP6125

グリオキサラーゼI ヒト

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 別名: Aldoketomutase, GLO-1 methylglyoxalase, Glx 1, Lactoylglutathione lyase
• UNSPSCコード: 12352204
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• アッセイ: ≥90% (SDS-PAGE)
• 形状: liquid
• 分子量: 20.7 kDa (184 aa, 1-184 aa)
• 包装: pkg of 100 μg
• NCBIアクセッション番号: Q04760
• UniProtアクセッション番号: Q04760
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... GLO1(2739)

詳細

詳細

GLO1 is involved in the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutathione. GLO1 is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. GLO1 enzyme is abundantly expressed and present in numerous tumor cell lines, in which its concentration is often upregulated ubiquitously. GLO1 is a major susceptible gene for autism in an ethnic Chinese population from Taiwan. GLO1 might be involved in the pathophysiology of mood disorders. GLO1 plays a role in the pathophysiology of mood disorders. Overexpression of GLO1 is associated with kidney tumor.

物理的形状

1 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.

調製ノート

バイアルは、開封前に遠心してください。

その他情報

MAEPQPPSGG LTDEAALSCC SDADPSTKDF LLQQTMLRVK DPKKSLDFYT RVLGMTLIQK CDFPIMKFSL YFLAYEDKND IPKEKDEKIA WALSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKM ATLM

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H319
• 注意書き: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable